General Information

  • ID:  hor000345
  • Uniprot ID:  A0A1S4FBE9
  • Protein name:  Allatostatin C
  • Gene name:  NA
  • Organism:  Aedes aegypti (Yellowfever mosquito) (Culex aegypti)
  • Family:  Allatostatin family
  • Source:  animal
  • Expression:  NA
  • Disease:  NA
  • Comments:  NA
  • Taxonomy:  Stegomyia (subgenus), Aedes (genus), Aedini (tribe), Culicinae (subfamily), Culicidae (family), Culicoidea (superfamily), Culicomorpha (infraorder), Nematocera (suborder), Diptera (order), Endopterygota (cohort), Neoptera (infraclass), Pterygota (subclass), Dicondylia, Insecta (class), Hexapoda (subphylum), Pancrustacea, Mandibulata, Arthropoda (phylum), Panarthropoda, Ecdysozoa, Protostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
  • GO MF:  NA
  • GO BP:  NA
  • GO CC:  NA

Sequence Information

  • Sequence:  QIRYRQCYFNPISCF
  • Length:  15(101-115)
  • Propeptide:  MLSTSMSSRQILLGLALLLCVVKLTTGRPQNAIDNQDAPEINLNELRKLYSNYNPYVSNSLDDYGLDRLQLQLLAQYAQSNAIGGAGGWDQLYRAPEMKRQIRYRQCYFNPISCFKK
  • Signal peptide:  MLSTSMSSRQILLGLALLLCVVKLTTG
  • Modification:  NA
  • Glycosylation:  NA
  • Mutagenesis:  NA

Activity

  • Function:  NA
  • Mechanism:  NA
  • Cross BBB:  NA
  • Target:  NA
  • Target Unid:  NA
  • IC50: NA
  • EC50: NA
  • ED50: NA
  • kd: NA
  • Half life: NA

Structure

  • Disulfide bond:  NA
  • Structure ID:  NA
  • Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)
  •    hor000345_AF2.pdbhor000345_ESM.pdb

Physical Information

Mass: 218814 Formula: C88H128N24O22S2
Absent amino acids: ADEGHKLMTVW Common amino acids: CFIQRY
pI: 8.78 Basic residues: 2
Polar residues: 6 Hydrophobic residues: 4
Hydrophobicity: -32.67 Boman Index: -3288
Half-Life: 0.8 hour Half-Life Yeast: 10 min
Half-Life E.Coli: >10 hour Aliphatic Index 52
Instability Index: 2066 Extinction Coefficient cystines: 3105
Absorbance 280nm: 221.79

Literature

  • PubMed ID:  20163154
  • Title:  Neuropeptidomics of the Mosquito Aedes Aegypti